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Scripps: Breaking COVID-19’s “clutch” may stop spread


Scripps Research chemist Matthew Disney, Ph.D., and colleagues have created drug-like compounds that, in human cell studies, bind and destroy the pandemic coronavirus’ so-called “frameshifting element” to stop the virus from replicating. The frameshifter is a clutchlike device the virus needs to generate new copies of itself after infecting cells. “Our concept was to develop lead medicines capable of breaking […]

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